What is CO2 Lift or Carboxy Therapy?

CO2 Lift or Carboxytherapy is the Therapeutic Use of Carbon Dioxide for Skin Regeneration

When infused into the skin, CO2 immediately diffuses at the cutaneous and muscular microcirculatory levels, resulting in higher tissue oxygenation and neoangiogenesis. The blood vessels widen, increasing the transport of oxygen body tissues for cellular regeneration and anti-inflammatory effects.

It is a treatment that has been around since the 1930s, though the method of delivery has improved since then, with a gel delivery system, CO2Lift!

Carboxytherapy uses carbon dioxide to stimulate blood and lymph circulation to the area being treated and improve circulation, elasticity, fine lines and wrinkles.

The old way to administer carboxytherapy is by subdermal injection of CO2 with a thin high-gauge needle.

This application causes little pain and discomfort and leaves minor bruising.

CO2 Lift PRO kit

Topical Carboxy Therapy: CO2Lift

Today, topical carboxy therapy brings the benefits of carbon dioxide infusion without any injection required. CO2Lift Carboxy therapy was developed to harness the human body’s natural response to carbon dioxide.

  • Increasing the presence of wound repair factors and growth factors, which help cells “turn over” faster, reducing the appearance of aging, scars, stretch marks and more.
  • Stimulating collagen and elastin production, which promotes elasticity and helps retain hydration.
  • Improving local metabolism and elimination of waste products, which helps the body heal localized damage such as scars or acne hyperpigmentation.
  • Regenerating and repairing damaged tissue to help clients achieve better looking and feeling skin.

What is CO2Lift Carboxytherapy Gel?

A take-home treatment created in 2015 that maximizes chair time and is proven to have similar results to injections.*

  • Beneficial to all providers: surgical, aesthetic, medical, and aestheticians.
  • Powerful anti-aging and aesthetic solution designed for face, eyes, body and vagina.
  • Regenerates the vulva/vaginal tissue and reduces the symptoms of GSM.***
  • Effective for healing diabetic ulcers in as little as 4 treatments.****
  • Focuses on solving an individual’s aging skin without the use of machines, aggressive peels, injections, or cosmetic surgery.

* Leibascoff, G, Roberts W, Coll L, 2018 Surgical Tech Int
** Biometrrix 2017 Hydration Study
*** Leibaschoff G, Reyes C, Arrieta C, Melamed J, 2021 Surgical Tech Int.

Carboxytherapy Effects

  • Vasodilation*

  • Increase in Flow Motion*

  • Increase in Growth Factors (e.g. VEGF)

  • Increase in Microcirculation

  • Increase in Neoangiogenesis

  • Increase in tissular oxygenation/[PO2] Bohr Effect**

  • Neoprocollagenesiss

  • Correction of PH

  • Cleaning of the ECM for improved tissue health***

  • Biostimulation of the connective tissue****

  • Resoration of the microvascular-tissular unit exchanges*****

Not only do patients experience increased healing of their primary burns, they experience significant improvements to the appearance of their skin. Those improvements included:

  • Reduced fine lines
  • Improved wrinkles
  • Smaller pores
  • Firmer texture

The results were clear—cutaneous carboxytherapy gel had potential for powerful use in anti-aging skincare.

* Hartmann BR, Bassenge E Angiology 48:337, 1997 • Abramo AC Rev Bras Cir Plast, 2009 • Varlaro V Blood 2007
** Vacher, 1987
*** Maia-Figueiró TL, ODashire AN, Menezes GP
**** Ferreira JCT J Drugs Dermatol, 2008

So, How Does It Work?

What is the Mechanism of Action?

The energy necessary for cell division and cell activation is produced by the increase of oxygen.

CO2 Skin Absorption: The absorption of CO2 leads to a deficiency of oxygen beneath the skin causing the body to supply more oxygen to the area.

Expansion of Capillaries: Blood bringing the additional oxygen to the area causes the blood vessels to expand.

Supply of Oxygen and Nutrients to the Cells: This oxygen-rich blood supplies nutrients and immunoregulatory substances to the cells.

How Is the CO2 Created?: When the water in the large packet mixes with the gluconolactone in the small packet, it forms a mild acid. That mild acid mixes with the magnesium carbonate to form CO2. The resulting CO2 is absorbed into the skin in a unique, hypoallergenic, and mild treatment.

CO2 Lift PRO Diagram

Contact Rejuvenate 528 Med Spa Today!


Treatment hours: Monday 12p – 8pm, Tuesday, Thursday and Fridays 11am – 8pm

We offer Cherry Payment Plans and CareCredit® Financing

Be sure to register for the Alle program and the Xperience Program for additional savings

Schedule a Complimentary Consultation

CO2 Lift PRO

The CO2LiftPro is the strongest version on carboxy gel only available to Aesthetic and Medical Providers.

It is an in-office or at-home treatment that delivers CO2 cutaneously over 35 minutes to an hour. This transdermal, noninvasive facial mask is recommended for post-procedure care after invasive procedures such as needling or laser.

In one use, the CO2LiftPro mask:

  • Speeds healing
  • Boosts oxygen concentration

  • Increases microcirculation

  • Tightens skin appearance

  • Reduces pore size

  • Smooths skin texture

  • Increase skin hydration by 117%+

CO2 Lift Facial Treatment

CO2LiftPro as a Medical Monotherapy

Clinical studies of topical carboxytherapy show dramatically increased hydration by 117% compared to baseline post treatment for up to 3 weeks.

Medical uses of topical carboxytherapy:

  • Severely dry skin
  • Itchy skin
  • Speedy healing of wounds
  • Increase blood flow

CO2LiftPro as an Aesthetic Monotherapy

Aesthetic uses of topical carboxytherapy:

  • Fine Lines/Wrinkles
  • Crêpey Skin
  • Dark Circles
  • Inflamed Skin
  • Textural Imbalances
  • Dehydration
  • Enlarged Pores
  • Dull Tone

Safe when applied to upper eyelids and on mucosal membranes.

CO2LiftPro For Energy-Based Treatments

Medical grade topical Carboxytherapy Gel is proven safe to use pre- or post-procedure for:

  • Less pain during treatment
  • Reduced complications
  • Reduced downtime
  • Improved procedural outcomes
  • Improved patient experience
  • Reduced post-treatment side effects

CO2 LiftV

CO2 LiftV is a take-home vaginal rejuvenation treatment.

It can improve the symptoms of genito-urinary syndrome of menopause (GSM) as well as patients report reduction in symptoms of lichen sclerosus. Many women report significant improvement in the following conditions:

  • Dryness
  • Burning
  • Itching
  • Pain during sex
  • Post-coital bleeding
  • Loss of sensitivity
  • Vaginal Laxity
  • Urinary Incontinence
  • Cosmetic appearance

The majority of women face pain or discomfort during sex as a normal part of the decreasing estrogen levels. The onset of GSM signals a sharp drop in estrogen in perimenopause that continues into menopause and postmenopause.

This decrease in estrogen causes changes in skin elasticity and collagen production, affecting the labia minora and majora, clitoris, and vagina; as well as decreasing skin hydration.

Other women affected by similar changes include women breast feeding, post-hysterectomy, women who take medication with sexual side effects, or women with endocrine disorders.

CO2LiftV is a gel applied topically to the vulva and as a vaginal suppository using the included syringe. Each treatment is noninvasive, private, and takes only 45 minutes or it can be left on overnight.

This carboxytherapy vaginal gel is effective at reducing recovery time and improving healing in post-procedure patients, including post-episiotomy, post-childbirth trauma, and post-labiaplasty patients. Vaginal Laxity

Who Is CO2 LiftV For?

CO2LiftV can be for every woman:

  • Women for self-care and general intimate health
  • New Mothers
  • Menopausal Women
  • Women on prescription medication
  • Women concerned about the vulva’s cosmetic appearance
  • Women who have had chemotherapy
  • Women with a history of breast cancer who have GSM symptoms but cannot take estrogen
  • Women with Lichen Schlerosus
  • Women with PCOS
CO2 V Lift kit

CO2LIFTV is a painless effective treatment that, with no downtime, addresses vaginal issues associated with aging, childbearing and/or stress.

Our Kit comes with 5 treatments and can be used in the privacy of your home. After just one application users will feel and see results. Doctors recommend 10-15 treatments for long lasting results, that can be maintained by monthly treatments.

  • Produces Natural Lubrication
  • May Improve Vaginal Tightening
  • May Reduce Painful Intercourse
  • Enhances Cosmetic Appearance
  • May Increase Sensation

Before mixing the large and small pack in a small bowl, massage the small packet to soften it. After mixing thoroughly with mixing stick for about 1 minute, push the gel together in the bowl. Use applicator to pull up the gel. Insert into vagina and on vulva. Apply 2/3 of the gel into the vagina. The rest apply to vulva. Leave on for 45 minutes minimum. You can leave on overnight. Rinse out of vagina by filling applicator with water. Do this about 3 times. Wash off the vulva. Pat dry.

Do this treatment every 5 to 7 days or as recommended by your Provider. Then you can maintain with monthly treatments.

These statements have not been evaluated by the Food and Drug Administration (FDA). Use only as directed. This product is not intended to diagnose, treat, cure, or prevent any disease or as a prescription for medication. Please read all packaging and labels carefully. Always consult your physician or health care provider before taking any supplement. If you have or suspect that you have a medical problem, please consult your physician or health care provider.

Contact Rejuvenate 528 Med Spa Today!


Treatment hours: Monday 12p – 8pm, Tuesday, Thursday and Fridays 11am – 8pm

We offer Cherry Payment Plans and CareCredit® Financing

Be sure to register for the Alle program and the Xperience Program for additional savings

Schedule a Complimentary Consultation

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