Stem Cell Growth Factors and Cytokines
Our Stem Cells make hundreds of Growth Factors & Cytokines, functioning as signaling molecules from cell to cell and instructing the metabolic machinery within cells. Growth Factors have been established as some of the highest level of optimization in anti-aging skincare currently.
Bio-signals produced from laboratory culture of different cell types vary greatly: some are anti-aging, while others are actually pro-aging. Multiple peer reviewed studies have determined that lab cultured Growth Factors & Cytokines derived from adult human bone marrow stem cells are primarily anti-inflammatory and anti-aging, beneficial to the skin.
What is a Stem Cell?
The simplest explanation of what a stem cell is, is a cell that can either replicate itself (turning into new versions of itself), or a cell that can differentiate (turning into another type of cell or tissue). Stem cells are very complex cells and very beautiful in their ability to achieve a lot of coordinated healing inside the entire body. Stem cells and stem cell research are in an area of medicine known as regenerative medicine, which is essentially the science of your body’s natural ability to heal itself. Stem cells play a vital role in regenerative medicine.
There are several growth factors and cytokines that the bone marrow stem cell produces in abundance. Some of these proteins are widely utilized in regenerative medicine, and play a critical role when it comes to aesthetics and wound healing– especially in an anti-inflammatory environment– all of which can be found in the bone marrow stem cell secretome and are the same growth factors what would be used topically.
What are Growth Factors?
To put it simply… Growth factors are naturally occurring proteins that regulate cellular growth, healing, proliferation and differentiation under controlled conditions.
Growth factors typically act as signaling molecules between cells. Meaning they are a part of cellular communication.
Please note that Growth Factors are not Growth Hormones and do not have the same effects.
What we have found is that Growth factors play a pivotal role in maintaining firmness and elasticity in your skin and other tissues. It has been shown that cells in aging skin make less growth factors than cells in youthful skin. For example, by the time you are 50 years old, you only have around 4% of circulating bone marrow mesenchymal stem cells, which are responsible for emitting your own growth factors to repair the body naturally.
How do growth factors work?
Growth factors work by stimulating biochemical pathways that promote skin tissue repair and regeneration. They promote the formation of collagen and elastic fibers which give the skin its softness and suppleness.
Synergistic interaction of multiple growth factors with other proteins in epidermis and dermis results in skin repair and regeneration.
It is important to know that no single growth factor is solely determinant in the outcome of skin rejuvenation.
Successful repair of damaged skin and collagen synthesis require the involvement of growth factors and cytokines.
What are Cytokines?
The term “cytokine” is derived from a combination of two Greek words – “cyto” meaning cell and “kinos” meaning movement.
Cytokines are a broad and loose category of small signaling molecules that aid cell to cell communication in immune responses and stimulate the movement of cells towards sites of inflammation, infection and trauma. There they regulate a wide range of biological functions including innate and acquired immunity, hematopoiesis, inflammation and repair, and proliferation through mostly extracellular signaling.
Cytokines act via binding to a receptor that in turn sends a signal to the recipient cell, leading to a change in function or phenotype. This is especially important in the immune system; cytokines modulate the balance between humoral and cell-based immune responses, and they regulate the maturation, growth, and responsiveness of particular cell populations.
The most current terminology used to describe cytokines is “immuno-modulating agents” or agents that modulate or alter the immune system response. Cytokines are important regulators of both the innate and adaptive immune response.
We now know that daily use of skin care products containing growth factors and cytokines are known to help reduce the appearance of fine lines, wrinkles and improve skin tone and texture.
When used in conjunction with needling or injection they are even more effective than when used in topical creams alone.
Stem Cell Growth Factors & Cytokines Now Available for Procedures and Products
Now available to you are products and procedures which contain high concentrations of stem cell growth factors & cytokines. Including Microneedling, Hair Regeneration, Skin Care, Home Needling Kits, Hair Kits, Vaginal Rejuvenation and more.
Mesenchymal stem cells originating from bone marrow are the most powerful and versatile population in your body, able to transform into myriad of cell types to fight injury and inflammation. As they leave the bone marrow and travel throughout the body, these stem cells act as command and control centers, directing the process of healing to minimize overall damage. We can’t live without these cells, and yet we have fewer of them working for us with each passing day.